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Measurands

This section provides information on the status of harmonization or standardization of measurands. Priorities based on medical impact are provided for measurands for which harmonization is needed or that have an incomplete or inactive implementation of a harmonization activity.  Additional information regarding the harmonization status and medical impact is available by clicking on the measurand name. Information on reference materials, reference measurement procedures, and reference laboratory services is provided by the links in the JCTLM column. Links to organizations actively addressing harmonization of particular measurands are provided for additional information on those projects.

Comments on measurand status can be sent using the Contact Us tab.         Download the form to submit a new measurand.


Summary of Measurand Harmonization Activities

The measurand table is a dynamic information resource. Check regularly for new information.

Click on a measurand to see additional information regarding harmonization status and medical impact.

Click on a JCTLM component or an organization link for information on those resources.

Click on a single column to sort the table.

Download the measurand table as PDF file
Measurand Matrix Medical Impact of Harmonization1 Harmonization Status2 JCTLM Listed3 Organization
Akaline Phosphatase (ALP) Serum Medium Incomplete IFCC  
Alanine Aminotransferase (ALT) Serum Medium Incomplete IFCC   EU-JRC (IRMM)  
Albumin Serum Medium Needed  
Albumin Urine Active NKDEP   IFCC   JSCC  
Amylase Serum Active IFCC  
Anti-Hepatitis C Virus antibody (Anti-HCV Ab) Serum Adequate  
Aspartate Aminotransferase (AST) Serum Medium Incomplete IFCC  
Bilirubin, conjugated Serum Medium Needed  
Bilirubin, total Serum Adequate  
Blood gasses (pH, pO2, pCO2, oximitry) Blood Adequate  
B-type Natriuretic Peptide (BNP) Serum High Needed  
CA 125 Serum High Needed  
CA 15-3 Serum High Needed  
CA 19-9 Serum High Needed  
Calcium Serum Adequate  
Carbohydrate-deficient transferin (CDT) Serum Active IFCC  
Carcinoembrionic antigen (CEA) Serum High Needed  
Chloride Serum Adequate  
Cholesterol, HDL Serum High Incomplete CDC  
Cholesterol, LDL Serum Medium Incomplete CDC  
Cholesterol, total Serum Adequate CDC  
C-Peptide Serum Active University of Missouri   National Metrology Institute of China   JCCLS  
C-Reactive protein, high sensitivity Serum Adequate  
C-Reactive protein, inflammatory Serum Low Incomplete EU-JRC (IRMM)  
Creatine Kinase (CK) Serum Incomplete IFCC   EU-JRC (IRMM)  
Creatine Kinase-MB (CK-MB) Serum Adequate  
Creatinine Serum Adequate  
CSF Proteins CSF Active IFCC  
Cytomegalovirus (CMV) Plasma Medium Needed  
Cytomegalovirus IgG (CMV IgG) Serum Adequate  
Epstein-Barr Virus Blood Active National Cancer Institute, NIH, USA  
Ethyl Alcohol Serum, Plasma Adequate  
Folate Serum Active CDC   NIST  
Fructosamine Serum Adequate  
Gamma glutamyl transferase (GGT) Serum Adequate  
Glucose Serum Adequate  
Glucose (POCT) Blood Adequate  
Glycated Albumin Serum Adequate  
Growth Hormone Serum Active IFCC  
HBV Ag and anti-HBs Ab Serum Adequate  
Hemoglobin A1c (HbA1c) Blood Adequate IFCC   NGSP  
Hemoglobin A2 (HbA2) Serum Active IFCC  
Hepatitis C Virus RNA Serum Adequate  
HIV-1 Ag with HIV-1 and HIV-2 Abs Serum Adequate  
HIV-RNA Serum, Plasma Adequate  
Human Chorionic Gonadotropin (hCG) Serum High Needed  
IgG antibodies to myeloperoxidase Serum Active  
Insulin Serum Active IFCC   ADA   EASD  
Iron binding capacity (unsaturated ) Serum Adequate  
Lactate Serum Adequate  
Lactate Dehydrogenase (LDH) Serum Incomplete IFCC   IRMM  
Lipase Serum Active IFCC  
Lithium Serum, Heparin Plasma Adequate  
Magnesium Serum Adequate  
Myoglobin Serum, Urine Adequate  
NT-proBNP Serum Adequate  
pancreatic lipase Serum Active IFCC  
Parathyroid hormone (PTH) Serum Active IFCC  
Phosphate Serum Adequate  
Potassium Serum Adequate  
Pregnancy-Associated Plasma Protein A Plasma Active IFCC  
Prostate Specific Antigen (PSA) Serum High Needed  
Protein, total Serum Adequate  
Rheumatoid factor (RF) Serum Low Needed  
Sodium Serum Adequate  
Thyroid stimulating hormone (TSH) Serum Active IFCC  
Thyroxine (T4) Serum Active IFCC  
Thyroxine, free (FT4) Serum Active IFCC  
Treponema pallidum (syphilis) Serum Adequate  
Triglycerides Serum Adequate CDC  
Triiodothyronine, free (FT3) Serum High Needed  
Troponin I, cardiac (cTnI) Serum Active IFCC  
Troponin T Serum Adequate  
Urea N (BUN) Serum Adequate  
Uric acid Serum Adequate  
Vancomycin Serum High Needed  

Low, medium and high refer to the medical impact of the current inadequate harmonization on potential medical errors in interpreting a result for a measurand.

Harmonization status: Active means an organization is implementing a harmonization project; Adequate means the current harmonization is suitable for medical decisions; Inactive means a harmonization activity was started but is no longer being actively implemented; Incomplete means resources to achieve harmonization are available but have not been adequately implemented; Needed means no harmonization activity has been started but one is needed.

JCTLM abbreviations: RM, reference material; RMP, reference measurement procedure; RL, reference laboratory.